Baloxavir Marboxil 1985606-14-1

Tsanangudzo Pfupi

Zita reAPI Indication Innovator Patent Expiry Date (The US)
Baloxavir Marboxil 1985606-14-1 Furuwenza Shionogi & Roche Sep.21,2031


Product Detail

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PRODUCT DETAIL

Background

Baloxavir marboxil mushonga unorwisa hutachiona uye ndeye endonuclease inhibitor.Mumakonzo netsoko, huwandu hweropa hwemushonga hwakaderera pane hudiki hwekuonekwa huwandu mune imwechete yemuromo kutonga kwemushonga.Mune preclinical furuwenza A uye B mhando dzehutachiona (kusanganisira madhiri anoramba kune aripo antiviral mishonga), Baloxavir marboxil ine imwe mhedzisiro.

Chemical Properties

Storage Chengetedza pa -20°C
M.Wt 571.55
Cas Nha. 1985606-14-1
Formula C27H23F2N3O7S
Mashoko anoreva zvakafanana S-033188
Solubility Soluble muDMSO
Chemical Name ((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8, 12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl)oxy)methyl methyl carbonate
SDF Dhaunirodha SDF
Canonical SMILES O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46) F)C3=C1OCOC(OC)=O
Shipping Condition Evaluation sampuli mhinduro: ngarava ine bhuruu ice.Mamwe ese anowanikwa saizi: ngarava ine RT, kana yebhuruu ice kana uchikumbira.
General mazano Kuti uwane kunyungudika kwepamusoro, ndapota dziisa chubhu pa 37 ° C uye uizununguse mu ultrasonic bath kwechinguva.Stock solution inogona kuchengetwa pazasi -20°C kwemwedzi yakati wandei.

Chimiro chemakemikari

Baloxavir-Marboxil-1985606-14-1

CERTIFICATE

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

HUNHU MANAGEMENT

Quality management1

Proposal18Quality Consistency Evaluation mapurojekiti akatenderwa4,uye6mapurojekiti ari pasi pekubvumidzwa.

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Yepamberi yepasirese yemhando manejimendi system yakaisa hwaro hwakasimba hwekutengesa.

Quality management3

Kutariswa kwemhando yepamusoro kunofamba kuburikidza nehupenyu hwese kutenderera kwechigadzirwa kuti ive nechokwadi chemhando nekurapa.

Quality management4

Professional Regulatory Affairs timu inotsigira zvinodiwa zvemhando panguva yekushandisa uye kunyoreswa.

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