Baloxavir Marboxil 1985606-14-1
Background
Baloxavir marboxil is antiviral drug uye is endonuclease inhibitor. Mumakonzo netsoko, kuwanda kweropa kwemushonga kwakadzikira pane diki yekuona huwandu mune imwechete yemuromo kutonga kwemushonga. Mune preclinical furuwenza A uye B mhando dzehutachiona (kusanganisira madhiri anoramba kune aripo antiviral mishonga), Baloxavir marboxil ine imwe mhedzisiro.
Chemical Properties
| Storage | Chengetedza pa -20°C |
| M.Wt | 571.55 |
| Cas Nha. | 1985606-14-1 |
| Formula | C27H23F2N3O7S |
| Mashoko anoreva zvakafanana | S-033188 |
| Solubility | Soluble muDMSO |
| Chemical Name | ((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8 ,12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl)oxy) methyl carbonate |
| SDF | Dhaunirodha SDF |
| Canonical SMILES | O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46) F)C3=C1OCOC(OC)=O |
| Shipping Condition | Evaluation sampuli mhinduro: ngarava ine bhuruu ice. Mamwe ese anowanikwa saizi: ngarava ine RT, kana yebhuruu ice kana uchikumbira. |
| General mazano | Kuti uwane kunyungudika kwepamusoro, ndapota dziya chubhu pa 37 ° C uye uizununguse mu ultrasonic bath kwechinguva. Stock solution inogona kuchengetwa pazasi -20°C kwemwedzi yakati wandei. |
Chimiro chemakemikari
Proposal18Quality Consistency Evaluation mapurojekiti akatenderwa4,uye6mapurojekiti ari pasi pekubvumidzwa.
Yepamberi yepasirese yemhando manejimendi system yakaisa hwaro hwakasimba hwekutengesa.
Kutariswa kwemhando yepamusoro kunomhanya kuburikidza nehupenyu hwese kutenderera kwechigadzirwa kuti ive nechokwadi chemhando uye yekurapa maitiro.
Professional Regulatory Affairs timu inotsigira zvinodiwa zvemhando panguva yekushandisa uye kunyoreswa.
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