Chlorothiazide

Tsanangudzo Pfupi

Zita reAPI Indication Tsanangudzo US DMF EU DMF CEP
Chlorothiazide Diuretics USP/EP      


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PRODUCT DETAIL

Background

Chlorothiazide inhibitor yecarbonic anhydrase uye ine simba zvishoma pane acetazolamide.Mushonga uyu wakaratidzwa kudzivirira kudzoreredzwa kwesodium uye chloride ions.

Tsanangudzo

Chlorothiazide ine diuretic uye antihypertensive.(IC50=3.8 mM) Chinangwa: Zvimwe Chlorothiazide sodium (Diuril) mushonga unoshandiswa mukati mechipatara kana kuti kuzvishandisa iwe pachako kugadzirisa mvura yakawandisa ine chekuita ne congestive heart failure.Inoshandiswawo se antihypertensive.Kazhinji kazhinji inotorwa mufomu yepiritsi, inowanzotorwa nemuromo kamwe kana kaviri pazuva.Mugadziriro yeICU, chlorothiazide inopiwa kupatsanura murwere kuwedzera kune furosemide (Lasix).Kushanda mune imwe nzira pane furosemide, uye yakanyura mukati seyakagadziriswazve kuturika kunoitwa kuburikidza ne nasogastric chubhu (NG chubhu), iyo miviri mishonga inogona mumwe kune mumwe.

Clinical Muedzo

Nhamba yeNCT Sponsor Condition Zuva Rokutanga

Phase

NCT03574857 Yunivhesiti yeVirginia Kutadza Kwemoyo | Kutadza Kwemoyo Nekuderedzwa Ejection Fraction Chikumi 2018

Chikamu chechina

NCT02546583 Yale University | National Heart, Lung, uye Ropa Institute (NHLBI) Kutadza Kwemoyo Nyamavhuvhu 2015

Hazvigoneke

NCT02606253 Vanderbilt University|Vanderbilt University Medical Center Kutadza Kwemoyo Kukadzi 2016

Chikamu chechina

NCT00004360 National Center for Research Resources (NCRR)|Northwestern University|Hofisi yeZvirwere Zvisingawanzo (ORD) Chirwere cheshuga Insipidus, Nephrogenic Gunyana 1995

NCT00000484 National Heart, Lung, uye Ropa Institute (NHLBI) Cardiovascular Diseases| Zvirwere zveMwoyo|Hypertension | Vascular Diseases Kubvumbi 1966

Phase 3

Chimiro chemakemikari

Chlorothiazide

CERTIFICATE

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

HUNHU MANAGEMENT

Quality management1

Proposal18Quality Consistency Evaluation mapurojekiti akatenderwa4,uye6mapurojekiti ari pasi pekubvumidzwa.

Quality management2

Yepamberi yepasirese yemhando manejimendi system yakaisa hwaro hwakasimba hwekutengesa.

Quality management3

Kutariswa kwemhando yepamusoro kunofamba kuburikidza nehupenyu hwese kutenderera kwechigadzirwa kuti ive nechokwadi chemhando nekurapa.

Quality management4

Professional Regulatory Affairs timu inotsigira zvinodiwa zvemhando panguva yekushandisa uye kunyoreswa.

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DCS Control Room

PARTNER

Kudyidzana kwenyika dzose
International cooperation
Kushandira pamwe kwemumba
Domestic cooperation

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