Chlorothiazide

Tsananguro Pfupi:

Zita re API Chiratidzo Tsanangudzo US DMF  EU DMF  CEP
Chlorothiazide Diuretics USP / EP      

Chigadzirwa Chigadzirwa

Chigadzirwa Mateki

CHIDZIDZO CHIDZIDZO

Mhemberero

Chlorothiazide inhibitor yecarbonic anhydrase uye ine simba shoma zvishoma pane acetazolamide. Ichi chikamu chakaratidzirwa kuvharidzira kudzoreredza sodiyamu uye chloride ions.

Tsananguro

Chlorothiazide ndeye diuretic uye antihypertensive. (IC50 = 3.8 mM) Target: Vamwe Chlorothiazide sodium (Diuril) idhiuretisi inoshandiswa mukati mechipatara kana yekushandisa wega kugadzirisa yakanyanya mvura inosangana ne congestive moyo kutadza. Iyo inoshandiswawo seyehypertensive. Kazhinji kacho inotorwa mupiritsi fomu, inowanzo kutorwa nemuromo kamwe kana kaviri pazuva. Mune iyo ICU marongero, chlorothiazide inopihwa diurese murwere mukuwedzera kune furosemide (Lasix). Kushanda mune yakasarudzika mashandiro kupfuura furosemide, uye yakanyura mukati seyakagadziriswazve inomiswa inotungamirwa kuburikidza nasogastric chubhu (NG chubhu), iyo miviri mishonga inogona kukonana.

Kliniki Kuedzwa

NCT Nhamba Sponsor Mamiriro Kutanga Zuva

Chikamu

NCT03574857 Yunivhesiti yeVirginia Kukundikana Kwemwoyo | Kukundikana Kwemwoyo NeKunoderedzwa Ejection Fraction | Mwoyo Kukundikana Kwakasimba | Zvirwere zvemoyo Chikumi 2018

Chikamu 4

NCT02546583 Yale University | National Mwoyo, Mapapu, uye Ropa Institute (NHLBI) Kukundikana Kwemwoyo Nyamavhuvhu 2015

Hazvigoneke

NCT02606253 Vanderbilt University | Vanderbilt University Medical Center Kukundikana Kwemwoyo Kukadzi 2016

Chikamu 4

NCT00004360 National Center Yekutsvagisa Zviwanikwa (NCRR) | Northwestern University | Hofisi yeRare Zvirwere (ORD) Chirwere cheshuga Insipidus, Nephrogenic Gunyana 1995

NCT00000484 National Mwoyo, Lung, uye Ropa Institute (NHLBI) Cardiovascular Zvirwere | Mwoyo Zvirwere | Hypertension | Vascular Zvirwere Kubvumbi 1966

Chikamu 3

Chimiro chemakemikari

Chlorothiazide

CERTIFICATE

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

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