Enalapril Maleate
Background
Enalapril Maleate
Tsanangudzo
Enalapril (murume) (MK-421 (murume)), iyo inoshandiswa metabolite yeenalapril, inonzi angiotensin-inoshandura enzyme (ACE) inhibitor.
MuVivo
Enalapril (MK-421) iprodrug inowanikwa yeangiotensin-inoshandura enzyme (ACE) inhibitor kirasi yemishonga. Inokurumidza kushandiswa muchiropa kune enalaprilat mushure mekutonga kwemuromo. Enalapril (MK-421) ine simba, inokwikwidza inhibitor yeACE, iyo enzyme inokonzera kutendeuka kwe angiotensin I (ATI) kune angiotensin II (ATII). ATII inodzora BP uye chinhu chakakosha cheiyo renin-angiotensin-aldosterone system (RAAS). Enalapril inogona kushandiswa kurapa yakakosha kana renovascular hypertension uye symptomatic congestive heart failure.
Storage
| Upfu | -20°C | 3 years |
| 4°C | 2 years | |
| In solvent | -80°C | 6 mwedzi |
| -20°C | Mwedzi 1 |
Chimiro chemakemikari
Proposal18Quality Consistency Evaluation mapurojekiti akatenderwa4,uye6mapurojekiti ari pasi pekubvumidzwa.
Yepamberi yepasirese yemhando manejimendi system yakaisa hwaro hwakasimba hwekutengesa.
Kutariswa kwemhando yepamusoro kunomhanya kuburikidza nehupenyu hwese kutenderera kwechigadzirwa kuti ive nechokwadi chemhando uye yekurapa maitiro.
Professional Regulatory Affairs timu inotsigira zvinodiwa zvemhando panguva yekushandisa uye kunyoreswa.
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