Pitavastatin Calcium
| 匹伐他汀钙 | Pitavastatin | 147526-32-7 | Mumba |
| PI-5 | 3800-06-4 | Mumba | |
| PI-6 | 145516-11-4 | Mumba | |
| PI-7 | 121660-11-5 | Mumba |
Tsanangudzo
Pitavastatin Calcium (NK-104 hemicalcium) ine simba hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis kubva acetic acid ine IC50 ye5.8 nM muHepG2 masero. Pitavastatin Calcium inoshanda hepatocyte yakaderera-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-gomarara basa.
Background
Pitavastatin Calcium inokwikwidza inhibitor ye enzyme HMGCR (HMG-CoA reductase) inoguma nekuderedza kweLDL cholesterol synthesis. Zvimwe zvidzidzo zvinoratidza kuti pitavastatin inogona kudzvinyirira kugadzirwa kweokisijeni mumasero endothelial nekudzivisa NADPH oxidase. Pamusoro pezvo, pitavastatin inoderedza kutaura kweNOS mRNA uku ichiwedzera NO inotsamira mhinduro inokurudzirwa neacetylcholine uye calcium ionophore, A23187. Uyezve, pitavastatin inhibits up-regulation of conductance calcium-activated potassium channels nekuderedza cholesterol mumasero.
Storage
4°C, kudzivirira kubva kuchiedza
*In solvent : -80°C, mwedzi mitanhatu; -20°C, mwedzi 1 (dzivirira kubva kuchiedza)
Chimiro chemakemikari
Related Biological Data
Proposal18Quality Consistency Evaluation mapurojekiti akatenderwa4,uye6mapurojekiti ari pasi pekubvumidzwa.
Yepamberi yepasirese yemhando manejimendi system yakaisa hwaro hwakasimba hwekutengesa.
Kutariswa kwemhando yepamusoro kunomhanya kuburikidza nehupenyu hwese kutenderera kwechigadzirwa kuti ive nechokwadi chemhando uye yekurapa maitiro.
Professional Regulatory Affairs timu inotsigira zvinodiwa zvemhando panguva yekushandisa uye kunyoreswa.
Korea Countec Bottled Packaging Line
Taiwan CVC Bottled Packaging Line
Italy CAM Board Packaging Line
German Fette Compacting Machine
Japan Viswill Tablet Detector
DCS Control Room
