Pomalidomide, yaimbozivikanwa seCC-4047 kana actimid, ine simba immunomodulatory molecule inoratidza antineoplastic chiitiko chekurapa hematological malignancies, kunyanya kudzoka uye refractory multiple myeloma (MM). Sezvinobva kune thalidomide, pomalidomide ine chimiro chemakemikari yakafanana sethalidomide kunze kwekuwedzerwa kwemapoka maviri oxo mumhete yephthaloyl uye boka reamino panzvimbo yechina. Kazhinji, se immunomodulatory molecule, pomalidomide inoratidza antitumor chiitiko kuburikidza nenzira yekuvharira bundu microenvironment nekugadzirisa tumor-inotsigira cytokines (TNF-α, IL-6, IL-8 uye VEGF), zvakananga pasi-kutonga mabasa akakosha ebundu. masero, nerutsigiro rwunobata kubva kune asiri-immune host masero.

Pomalidomide inoshandiswa kurapa akawanda myeloma (gomarara rinobva kuchirwere cheropa chinopfuurira). Pomalidomide inowanzopiwa mushure mekunge mimwe mishonga miviri yaedzwa pasina kubudirira.

Pomalidomide inoshandiswawo kurapa Kaposi sarcoma ine chekuita neAIDS apo mimwe mishonga haina kushanda kana kumira kushanda. pomalidomide inogonawo kushandiswa kurapa Kaposi Sarcoma kune vanhu vakuru variHIV-negative.

Pomalidomide inowanikwa chete kubva kuchitoro chemishonga pasi pechirongwa chakakosha. Iwe unofanirwa kunyoreswa muchirongwa uye kubvuma kushandisakudzora kuberekazviyero sezvinodiwa.

Pomalidomide inogona zvakare kushandiswa kune zvinangwa zvisina kunyorwa mugwaro remishonga.

Pomalidomide inogona kukonzera kuremara kwakakomba, kunotyisidzira hupenyu kana kufa kwemwana kana amai kana baba vari kutora pomalidomide panguva yekunamba kana panguva yekuzvitakura. Kunyange chipimo chimwe chepomalidomide chinogona kukonzera kuremara kukuru kwemaoko nemakumbo emwana, mapfupa, nzeve, maziso, chiso, uye mwoyo. Usamboshandisa pomalidomide kana uri nepamuviri. Udza chiremba wako pakarepo kana nguva yako yanonoka uchitora pomalidomide.