Relugolix inoshandiswa kurapa kenza yeprostate muvarume.
Mazita eBrand: Orgovyx
Drug Kirasi: Antineoplastic - LHRH (GnRH) Anopikisa Pituitary Suppressants
Kuwanika: Kunyorerwa Kunodiwa
Nhumbu: Bvunza chiremba wako. Mushonga uyu unogona kukuvadza mwana asati aberekwa.
Lactation: Bvunza chiremba usati washandisa

Relugolix inowanikwa nemuromo, isiri-peptide gonadotropin-inoburitsa mahomoni (GnRH kana luteinizing hormone-releasing hormone (LHRH)) anopikisa, ane angangoita antineoplastic chiitiko. Relugolix inosunga nemakwikwi uye inovhara GnRH receptor mune anterior pituitary gland, izvo zvese zvinodzivirira GnRH kusunga kune GnRH receptor uye inhibisa secretion uye kuburitswa kweese maviri luteinizing hormone (LH) uye follicle stimulating hormone (FSH). Muvarume, kuvharirwa kweLH secretion kunodzivirira kusunungurwa kwe testosterone kubva kuLeydig masero mumatestes. Sezvo testosterone ichidikanwa kuchengetedza kukura kweprostate, kudzikisa mazinga e testosterone kunogona kutadzisa hormone-inotsamira kenza yeprostate cell kuwanda.

Relugolix inonzi gonadotropin-releasing hormone (GnRH) receptor antagonist inoshandiswa mukurapa akati wandei mahormone-inopindura mamiriro. Yakatanga kubvumidzwa muJapan muna 2019, pasi pezita rechiratidzo Relumina, kurapwa kwechiratidzo che uterine fibroids, uye nguva pfupi yadarika neUnited States 'FDA muna 2020, pasi pezita rechiratidzo Orgovyx, kurapwa kwegomarara reprostate. Relugolix yakadzidzwawo mukurapa kwechiratidzo che endometriosis. Relugolix ndiyo yekutanga (uye parizvino chete) inopihwa nemuromo GnRH receptor antagonist yakabvumidzwa kurapwa kenza yeprostate - marapiro akafanana senge [degarelix] anoda subcutaneous manejimendi - uye nekudaro inopa isingaremerwe nzira yekurapa kune varwere vangangoda kushanyirwa kukiriniki. kuitira kutungamirirwa nevashandi vehutano. Mukuwedzera kune kusununguka kwayo-kwe-kushandiswa, relugolix yakaratidzwa kuva yakakwirira mukuora mwoyo kwemazinga e testosterone kana ichienzaniswa ne [leuprolide], imwe androgen deprivation therapy inoshandiswa mukurapa kenza yeprostate.

Relugolix iGonadotropin Inoburitsa Hormone Receptor Antagonist. Iyo nzira yekuita relugolix yakafanana neGonadotropin Inoburitsa Hormone Receptor Antagonist, uye Cytochrome P450 3A Inducer, uye Cytochrome P450 2B6 Inducer, uye Breast Cancer Resistance Protein Inhibitor, uye P-Glycoprotein Inhibitor. Iyo physiologic mhedzisiro ye relugolix ndeye kuburikidza neYakaderera GnRH Secretion.

Chimiro chemakemikari