Remdesivir mushonga unorwisa hutachiona unonangana nemhando dzakasiyana dzehutachiona. Yakatanga kugadzirwa makore gumi apfuura kurapa hepatitis C uye hutachiwana hunotonhora hunodaidzwa kuti respiratory syncytial virus (RSV). Remdesivir yanga isiri mushonga unoshanda kune chero chirwere. Asi yakaratidza vimbiso kune mamwe mavhairasi.

Vatsvagiri vakaedza remdesivir mumakiriniki miedzo panguva yekubuda kweEbola. Mimwe mishonga yekuongorora yakashanda zviri nani, asi yakaratidzwa kuva yakachengeteka kune varwere. Zvidzidzo mumaseru nemhuka zvakaratidza kuti remdesivir yaive inoshanda kurwisa mavhairasi mumhuri yekoronavirus, senge Middle East Respiratory Syndrome (MERS) uye Severe Acute Respiratory Syndrome (SARS).

Remdesivir inoshanda nekukanganisa kugadzirwa kwehutachiona. Coronaviruses ane genomes akaumbwa ribonucleic acid (RNA). Remdesivir inokanganisa imwe yeakakosha enzymes iyo hutachiona hunoda kudzokorora RNA. Izvi zvinoita kuti utachiona husawanda.

Vatsvagiri vakatanga muyedzo wakasarudzika, wakadzorwa weantiviral muna Kukadzi 2020 kuti vaone kana remdesivir inogona kushandiswa kurapa SARS-CoV-2, iyo coronavirus inokonzera COVID-19. Pakazosvika April,mhedzisiro yekutangayakaratidza kuti remdesivir yakamhanyisa kupora kwevarwere vari muchipatara vane yakanyanya COVID-19. Yakave mushonga wekutanga kugamuchira mvumo yekushandisa emergency kubva kuUS Food and Drug Administration (FDA) kurapa vanhu vari muchipatara neCOVID-19.

Vatsvagiri vapedza kuyedza, inozivikanwa seAdaptive COVID-19 Treatment Trial (ACTT-1). Ongororo iyi yakapihwa mari nesangano reNational Institute of Allergy and Infectious Diseases (NIAID). Chirevo chekupedzisira chakaonekwa muNew England Journal yeMishongamusi waGumiguru 8, 2020.