Tsanangudzo

Sugammadex sodium inogadzirwa neγ-cyclodextrin inotorwa, uye inoshanda sechinhu chitsva chinodzosera cheneuromuscular block.

Generic Zita: sugammadex (soo GAM ma dex)
Zita reBrand: Bridion

Sugammadex inodzosera mhedzisiro yeimwe mishonga inopihwa panguva yekuvhiya kuzorodza tsandanyama dzako.

Sugammadex inoshandiswa pakupera kwekuvhiyiwa, kubatsira kudzorera mhasuru basa rakavharwa panguva yekuvhiyiwa nemimwe mishonga.

Sugammadex inogona zvakare kushandiswa kune zvinangwa zvisina kunyorwa mugwaro remishonga.

Inoshandiswa kudzoreredza mhedzisiro yeimwe mishonga.

MuVivo

Jekiseni ye sugammadex haina mhedzisiro yakakosha paBP kana kurova kwemoyo.Mushure mejekiseni repamusoro rocuronium dose, iyo 90% kupora kwechitima-yechina chiyero inotora 28 min (SD 7 min) mushure mesaline, 26 min (SD 9.5 min) mushure me1 mg / kg sugammadex, uye 8 min (SD 3.6 min) mushure me2.5 mg / kg sugammadex [1].Sugammadex inokonzera kukurumidza uye kwakazara kutendeuka kwe rocuronium-induced neuromuscular block.Iyo yekudzoreredza nguva yekudzidzisa yechina chiyero = 0.9 mushure mekudzoreredza kupora ndeye 14.4 min (SD = 3.4 min; n = 14).Izvi zvakaderedzwa zvakanyanya kusvika ku3.7 min (SD = 3.3 min; n = 4) ne sugammadex 0.5 mg/kg uye ku1.9 min (SD=1.0 min; n = 4) ine sugammadex 1.0 mg/kg[2].Iyo inofungidzirwa hafu yehupenyu hwe sugammadex muRhesus monkey ndeye 30 (SEM = 4.9) min[3].

Storage

Chimiro chemakemikari