Rosuvastatin Calcium
| 瑞舒伐他汀钙 | Rosuvastatin Calcium | 147098-20-2 | Mumba/CEP |
| RSM(Crystal) | 147118-40-9 | Mumba | |
| RSM(Crude) | 147118-40-9 | Mumba | |
| RSP | - | Mumba | |
| RS-8 | 147118-36-3 | Mumba | |
| RS-8-1 | 147118-37-4 | Mumba | |
| TP-8 | 131466-61-0 | Mumba | |
| TP-11 | 147118-35-2 | Mumba | |
| TP-13 | 147118-39-6 | Mumba | |
| RS-10 | 289042-12-2 | Mumba | |
| RS-11 | 355806-00-7 | Mumba |
Tsanangudzo
Rosuvastatin Calcium (BANM, JAN, USAN) inozivikanwa seRosuvastatin muUS. uye inokwikwidza HMG-CoA reductase inhibitor ine IC50 ye11 nM[1]. Rosuvastatin Calcium inovhara zvine simba ether-a-go-go gene (hERG) yazvino ine IC50 ye195 nM, kunonoka kudzoreredzwa kwemoyo, uye nekudaro yakarebesa chiitiko chinogona kuita durations (APDs) uye kugadzirisa QT interval (QTc) nguva[2]. Rosuvastatin Calcium inoderedza kutaura kwehERG yakakura uye kupindirana kwekupisa kweprotein 70 (Hsp70) nehERG protein. Rosuvastatin Calcium inoshanda zvakanyanya mukudzikisa yakaderera-density lipoprotein (LDL) cholesterol, triglycerides, uye C-reactive protein mazinga[3].
Rumwe ruzivo pamusoro pezvibvumirano zvekupa mazita ezvinodhaka: International Nonproprietary Names.
Chiziviso Chakakosha: Iyo Drugs.com yepasi rose dhatabhesi iri mukuburitswa kweBETA. Izvi zvinoreva kuti ichiri kugadzirwa uye inogona kunge iine zvisizvo. Izvo hazvina kuitirwa sechinotsiva hunyanzvi uye kutonga kwachiremba wako, wezvemishonga kana imwe nyanzvi yehutano. Hazvifanirwe kutorwa kuratidza kuti kushandiswa kwemishonga chero ipi zvayo munyika ipi zvayo kwakachengeteka, kwakakodzera kana kunoshanda kwauri. Bvunza nyanzvi yako yezvehutano usati watora chero mushonga.
MuUS, Rosuvastatin (rosuvastatin systemic) inhengo yeboka rezvinodhaka statins uye inoshandiswa kurapa Atherosclerosis, High Cholesterol, High Cholesterol - Familial Heterozygous, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa - Yakakwira LDL, Hyperlipopro IIb - Yakakwira LDL VLDL, Hyperlipoproteinemia Rudzi rwechitatu - Yakasimudzwa beta-VLDL IDL, Hyperlipoproteinemia Rudzi IV - Yakasimudzwa VLDL, Hypertriglyceridemia uye Kudzivirira kweMwoyo weMwoyo Chirwere.
Background
Inosarudza, inokwikwidza inhibitor yeHMG-CoA reductase, iyo zvakare antilipemic.
Storage
| Upfu | -20°C | 3 years |
| 4°C | 2 years | |
| In solvent | -80°C | 6 mwedzi |
| -20°C | Mwedzi 1 |
Chimiro chemakemikari
Proposal18Quality Consistency Evaluation mapurojekiti akatenderwa4,uye6mapurojekiti ari pasi pekubvumidzwa.
Yepamberi yepasirese yemhando manejimendi system yakaisa hwaro hwakasimba hwekutengesa.
Kutariswa kwemhando yepamusoro kunomhanya kuburikidza nehupenyu hwese kutenderera kwechigadzirwa kuti ive nechokwadi chemhando uye yekurapa maitiro.
Professional Regulatory Affairs timu inotsigira zvinodiwa zvemhando panguva yekushandisa uye kunyoreswa.
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