Rosuvastatin Calcium
瑞舒伐他汀钙 | Rosuvastatin Calcium | 147098-20-2 | Mumba/CEP |
RSM(Crystal) | 147118-40-9 | Mumba | |
RSM(Crude) | 147118-40-9 | Mumba | |
RSP | - | Mumba | |
RS-8 | 147118-36-3 | Mumba | |
RS-8-1 | 147118-37-4 | Mumba | |
TP-8 | 131466-61-0 | Mumba | |
TP-11 | 147118-35-2 | Mumba | |
TP-13 | 147118-39-6 | Mumba | |
RS-10 | 289042-12-2 | Mumba | |
RS-11 | 355806-00-7 | Mumba |
Tsanangudzo
Rosuvastatin Calcium (BANM, JAN, USAN) inozivikanwa seRosuvastatin muUS.uye inokwikwidza HMG-CoA reductase inhibitor ine IC50 ye11 nM[1].Rosuvastatin Calcium inovhara zvine simba ether-a-go-go gene gene (hERG) ikozvino ine IC50 ye195 nM, inonoke cardiac repolarization, uye nekudaro inorebesa chiitiko chinogona kuita durations (APDs) uye kugadzirisa QT interval (QTc) nguva[2].Rosuvastatin Calcium inoderedza kutaura kwehERG yakakura uye kupindirana kwekupisa kweprotein 70 (Hsp70) nehERG protein.Rosuvastatin Calcium inoshanda zvikuru mukuderedza yakaderera-density lipoprotein (LDL) cholesterol, triglycerides, uye C-reactive protein mazinga[3].
Rumwe ruzivo pamusoro pezvibvumirano zvekupa mazita ezvinodhaka: International Nonproprietary Names.
Chiziviso Chakakosha: Iyo Drugs.com yepasi rose dhatabhesi iri mukuburitswa kweBETA.Izvi zvinoreva kuti ichiri kugadzirwa uye inogona kunge iine zvisizvo.Izvo hazvina kuitirwa sechinotsiva hunyanzvi uye kutonga kwachiremba wako, wezvemishonga kana imwe nyanzvi yehutano.Hazvifanirwi kutorwa kuratidza kuti kushandiswa kwemishonga chero ipi zvayo munyika ipi zvayo yakachengeteka, yakakodzera kana inoshanda kwauri.Bvunza nyanzvi yako yezvehutano usati watora chero mushonga.
MuUS, Rosuvastatin (rosuvastatin systemic) inhengo yeboka rezvinodhaka statins uye inoshandiswa kurapa Atherosclerosis, High Cholesterol, High Cholesterol - Familial Heterozygous, High Cholesterol - Familial Homozygous, Hyperlipoproteinemia, Hyperlipoproteinemia Type IIa - Yakakwira LDL, Hyperlipopro IIb - Yakakwira LDL VLDL, Hyperlipoproteinemia Rudzi rwechitatu - Yakasimudzwa beta-VLDL IDL, Hyperlipoproteinemia Rudzi IV - Yakakwirisa VLDL, Hypertriglyceridemia uye Kudzivirira kweMwoyo weMwoyo Chirwere.
Background
Inosarudza, inokwikwidza inhibitor yeHMG-CoA reductase, iyo zvakare antilipemic.
Storage
Upfu | -20°C | 3 years |
4°C | 2 years | |
In solvent | -80°C | 6 mwedzi |
-20°C | 1 mwedzi |
Chimiro chemakemikari
Proposal18Quality Consistency Evaluation mapurojekiti akatenderwa4,uye6mapurojekiti ari pasi pekubvumidzwa.
Yepamberi yepasirese yemhando manejimendi system yakaisa hwaro hwakasimba hwekutengesa.
Kutariswa kwemhando yepamusoro kunofamba kuburikidza nehupenyu hwese kutenderera kwechigadzirwa kuti ive nechokwadi chemhando nekurapa.
Professional Regulatory Affairs timu inotsigira zvinodiwa zvemhando panguva yekushandisa uye kunyoreswa.