Vericiguat is apyrazolopyridinendizvo5-fluoro-1H-pyrazolo[3,4-b]pyridineumo iyo amino hydrogen panzvimbo yekutanga yakatsiviwa ne2-fluorobenzyl boka uyehydrogenpanzvimbo 3 yakatsiviwa ne 4,6-diamino-5-[(methoxycarbonyl)amino]pyrimidin-2-yl boka.Inonyungudikaguanylatecyclase stimulator iyo inoshandiswa pakurapa kwekusingaperi kutadza kwemoyo.Iine basa rekunyungudikaguanylatecyclase activator, vasodilator agent uye antihypertensive agent.Icho chinhuaminopyrimidine, apyrazolopyridine, carbamate ester uye organofluorine compound.

Vericiguat iri kuferefetwa mukuedzwa kwekiriniki NCT02861534 (Chidzidzo cheVericiguat muVatori vechikamu Vane Kukundikana Kwemoyo Nekuderedzwa Ejection Fraction (HFrEF) (MK-1242-001)).

Vericiguat inonyungudikaGuanylateCyclase Stimulator.Iyo nzira yekuita yevericiguat yakaita seaGuanylateCyclase Stimulator.

Vericiguat mushonga unoshandiswa kubata uye kubata moyo kutadza neyakaderedzwa ejection chikamu (HFrEF).Inobatsira kune kusingaperi kuwedzera kuipa kwemoyo kukundikana, munguva pfupi yapfuura yakaderedzwa moyo kutadza.Vericiguat hairebedzi kurarama asi inodzivirira kudzorerwa muchipatara.Ichi chiitiko chinotaridza zviratidzo, maitiro echiito, chipimo chemushonga, uye maitiro ekutonga neboka renyanzvi, mhedzisiro, contraindication, uye miedzo yakati wandei kutsigira humbowo hwekubatsira kwemushonga muHFrEF.